Arrhythmias & electrophysiology
General anaesthesia compared to conscious sedation for first-time atrial fibrillation catheter ablation—a Danish nationwide cohort study
Main finding · AF recurrenceResult — go to the resultHazard ratio 1.26 95% CI 1.15–1.38Authors' conclusion
This nationwide cohort study suggests a higher risk of AF recurrence with CS during CA compared to GA.
Study context
- Population
- Adults (≥18 years) undergoing first-time catheter ablation for atrial fibrillation (AF) in Denmark, 2010–2018
- Participants
- 7,957 adults
- Exposure
- Conscious sedation vs general anaesthesia during first-time AF catheter ablation
- Conscious sedation (CS)n = 6,421
- General anaesthesia (GA)n = 1,536reference
- Outcome
- AF recurrence (composite:
- Antiarrhythmic drug prescriptions
- AF-related hospital admissions
- Electrical cardioversions
- AF re-ablation)
- Follow-up
- 5-year follow-up
Methodological detailsDanish healthcare registries, multivariable Cox proportional hazards analysis
- Danish healthcare registries
- Multivariable Cox proportional hazards analysis
Main finding
AF recurrence · 5 years
Hazard ratio
1.26
95% CI 1.15–1.38
By group
CSvs GA
HR 1.26 (95% CI 1.15–1.38)
As reported in the abstract
Observational data: associations, not effects.
Further findings
AF recurrence · 1 year · cumulative incidence
Original publication
General anaesthesia compared to conscious sedation for first-time atrial fibrillation catheter ablation—a Danish nationwide cohort study. Europace. Published 6 August 2024. doi:10. 1093/ europace/ euae203
Composed by AI from the published abstract and checked against it. How Briefs are made →