Valvular & structural heart disease
Geriatric Nutritional Risk Index Assessment in Patients Undergoing Transcatheter Edge-to-Edge Repair
Authors' conclusion
Regardless of MR etiology, GNRI is a useful predictor of short- and long-term mortality in patients undergoing TEER. Although TEER is effective for MR patients in malnourished states, further studies focused on the value of identifying and addressing malnutrition in this population are needed.
Study context
- Population
- Patients with mitral regurgitation (MR) who underwent transcatheter edge-to-edge repair (TEER)patients with MR who underwent TEER
- Participants
- 3,554 patients
- Exposure
- Procedural and clinical outcomes were compared between Geriatric Nutritional Risk Index (GNRI) groups
- Outcome
- Deaths during follow-up
- Follow-up
- Mean 586.8 ± 436.5 days
Main finding
As reported in the abstract
Median GNRI
92.3
Patients who died during follow-up
806
Observational data: associations, not effects.
Further findings
30-day mortality
- Thirty-day mortality
- 51 patients (1.4%)
- GNRI <82 group had the highest 30-day mortality rate
Prognosis by Kaplan-Meier across the 4 groups (entire cohort, functional MR, degenerative MR)
- Significantly better prognoses across the 4 groups
- P < 0.001
Risk of death (adjusted)
- Stepwise increase in risk of death in the GNRI 92 to 98, GNRI 82 to 92, and GNRI <82 groups compared to GNRI >98 as the reference
- After adjustment for multiple confounders
Original publication
Geriatric Nutritional Risk Index Assessment in Patients Undergoing Transcatheter Edge-to-Edge Repair. JACC Adv. Published 25 February 2025. doi:10.
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