Valvular & structural heart disease
Clinical Impact of Early Nutritional Reversibility After Mitral Valve Transcatheter Edge-to-Edge Repair
Authors' conclusion
The Δ-GNRI is a useful predictor of long-term prognosis, with reversibility observed in half of patients after M-TEER. Improvement in Δ-GNRI is associated with acute procedural success, underscoring the importance of assessing the potential for procedural success before M-TEER.
Study context
- Population
- Patients undergoing M-TEER for mitral regurgitation with Geriatric Nutritional Risk Index (GNRI) measured before and 1 month after, Japanese multicentre registry
- Participants
- 1,909 patients
- Exposure
- Improved GNRI vs worsening GNRI 1 month after M-TEER
- Outcome
- Long-term all-cause mortality or composite outcome
- Follow-up
- Median 1.3 years
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
As reported in the abstract
GNRI improved
54.8%
Deaths during follow-up
433
Observational data: associations, not effects.
Further findings
Factors associated with Δ-GNRI improvement
- Younger age, acute procedural success, lower high-sensitivity C-reactive protein, preprocedural high GNRI
- all P < 0.05
Original publication
Clinical Impact of Early Nutritional Reversibility After Mitral Valve Transcatheter Edge-to-Edge Repair. JACC Adv. Published 17 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →