Valvular & structural heart disease

GLIDE Score: Scoring System for Prediction of Procedural Success in Tricuspid Valve Transcatheter Edge-to-Edge Repair

JACC Cardiovasc ImagingPublished Prognostic model development and validation study

Authors' conclusion

The GLIDE score is a simple, 5-component score that is readily obtained during patient imaging and can predict successful T-TEER.

Study context

Population
Patients with tricuspid regurgitation (TR) undergoing T-TEER, January 2017–November 2022derivation
Participants
168 patients
Comparison
GLIDE score categories
Outcome
Immediate postprocedural TR reduction ≥2 grades and TR grade moderate or less
Follow-up
Immediate postprocedural
Methodological detailsderivation cohort at 2 centres, external validation cohort at 2 separate institutions, core laboratory assessment
  • Derivation cohort at 2 centres
  • External validation cohort at 2 separate institutions
  • Core laboratory assessment

Performance

As reported in the abstract

TR reduction ≥2 grades; TR grade moderate or less
Test or modelValueTR reduction ≥2 gradesTR grade moderate or less
GLIDE 0–1>90%
GLIDE ≥45.6%16.7%

Value

GLIDE 0–1>90%
GLIDE ≥4— not stated in the abstract

TR reduction ≥2 grades

GLIDE 0–1— not stated in the abstract
GLIDE ≥45.6%

TR grade moderate or less

GLIDE 0–1— not stated in the abstract
GLIDE ≥416.7%
External validation AUC
0.77 (95% CI: 0.69-0.86)

Further findings

Functional improvement (NYHA class, 6-minute walk distance) · 3 months

TR reduction significantly correlated with functional improvement

Original publication

GLIDE Score: Scoring System for Prediction of Procedural Success in Tricuspid Valve Transcatheter Edge-to-Edge Repair. JACC Cardiovasc Imaging. Published 5 June 2024. doi:10.1016/j.jcmg.2024.04.008

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