Arrhythmias & electrophysiology

Gradually increasing pacing impedances with normal sensing values in pacemaker and defibrillation leads: A watchful waiting strategy

Heart RhythmPublished single-center retrospective cohort study

Authors' conclusion

A watchful waiting strategy seems safe for patients without sensing or threshold concerns and in the absence of a pacing indication. A patient-centered approach should guide the management of gradual impedance increases in CIED leads.

Study context

Population
Patients with CIED leads showing a gradual increase in pacing impedance of >1200 Ωpatients, median follow-up 9.2 years (range 2.8–18.5)
Participants
59 patients
Exposure
Implantable cardioverter-defibrillator vs pacemaker
  • Implantable cardioverter-defibrillatorn = 42
  • Pacemakern = 17
Outcome
Lead preservation and replacement, implantable cardioverter-defibrillator

Main finding

As reported in the abstract

GroupValueReplacedReplaced prophylacticallyReplaced owing to oversensingReplaced for threshold issues
Implantable cardioverter-defibrillator78.6%9522

Implantable cardioverter-defibrillator

Value78.6%
Replaced9
Replaced prophylactically5
Replaced owing to oversensing2
Replaced for threshold issues2

Observational data: associations, not effects.

Further findings

Lead preservation and replacement, pacemaker
70.6% · 12 of 17 of 17

Original publication

Gradually increasing pacing impedances with normal sensing values in pacemaker and defibrillation leads: A watchful waiting strategy. Heart Rhythm. Published 25 August 2025. doi:10.1016/j.hrthm.2025.08.033

Composed by AI from the published abstract and checked against it. How Briefs are made →

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