Arrhythmias & electrophysiology
Gradually increasing pacing impedances with normal sensing values in pacemaker and defibrillation leads: A watchful waiting strategy
Authors' conclusion
A watchful waiting strategy seems safe for patients without sensing or threshold concerns and in the absence of a pacing indication. A patient-centered approach should guide the management of gradual impedance increases in CIED leads.
Study context
- Population
- Patients with CIED leads showing a gradual increase in pacing impedance of >1200 Ωpatients, median follow-up 9.2 years (range 2.8–18.5)
- Participants
- 59 patients
- Exposure
- Implantable cardioverter-defibrillator vs pacemaker
- Implantable cardioverter-defibrillatorn = 42
- Pacemakern = 17
- Outcome
- Lead preservation and replacement, implantable cardioverter-defibrillator
Main finding
As reported in the abstract
| Group | Value | Replaced | Replaced prophylactically | Replaced owing to oversensing | Replaced for threshold issues |
|---|---|---|---|---|---|
| Implantable cardioverter-defibrillator | 78.6% | 9 | 5 | 2 | 2 |
Implantable cardioverter-defibrillator
Value78.6%
Replaced9
Replaced prophylactically5
Replaced owing to oversensing2
Replaced for threshold issues2
Observational data: associations, not effects.
Further findings
- Lead preservation and replacement, pacemaker
- 70.6% · 12 of 17 of 17
Original publication
Gradually increasing pacing impedances with normal sensing values in pacemaker and defibrillation leads: A watchful waiting strategy. Heart Rhythm. Published 25 August 2025. doi:10. 1016/ j. hrthm. 2025. 08. 033
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