Cardio-oncology & other

Greenspace and Survival Among Older Women With Breast Cancer: Regional Variations Within the U.S. SEER-Medicare-Linked Database

JACC AdvPublished Surveillance, Epidemiology, and End Results-Medicare breast cancer (BC) cohort

Authors' conclusion

This study highlights the importance of investigating the relationship between greenspace and cardiooncology-related outcomes across regions, underscoring the need for more place-specific research to guide targeted interventions to improve survival outcomes.

Study context

Population
Women aged 66+ with invasive BC, enrolled in Medicare (Parts A and B) for 12 months prediagnosis and with known tract-level greenspace data, United Stateswomen included
Participants
86,300 women
Exposure
Greater percent tree canopy and survival
Outcome
Deaths during follow-up
Methodological details2010 to 2017, censoring by December 31, 2018
  • 2010 to 2017
  • Censoring by December 31, 2018

Main finding

As reported in the abstract

Died during the follow-up

22,541

26.1%

Died from BC, of those who died

9,012

40.6%

Died from cardiovascular disease (CVD), of those who died

4,195

18.9%

Observational data: associations, not effects.

Further findings

All-cause mortality (ACM)

HR (95% CI)
Greater percent tree canopyLower ACM with greater percent tree canopy0.90 (0.86–0.95)

BC-specific mortality (BCSM)

Cause-specific HR (95% CI)
Greater percent tree canopyLower BCSM with greater percent tree canopy0.90 (0.82–0.98)

Regional variations

Greenspace linked to lower ACM in California, New Jersey, and Michigan
Lower BCSM and CVD-specific mortality (CVDSM) in California and New Jersey
Washington, Louisiana, and Georgia showed nonsignificant or inconsistent results

Original publication

Greenspace and Survival Among Older Women With Breast Cancer: Regional Variations Within the U.S. SEER-Medicare-Linked Database. JACC Adv. Published 18 August 2025. doi:10.1016/j.jacadv.2025.102069

Composed by AI from the published abstract and checked against it. How Briefs are made →

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