Cardio-oncology & other

Operator Radiation Exposure Comparing the Left Radial Artery Approach and a Uniform Hyper-Adducted Right Radial Artery Approach: The Hyper-adducted Right Radial Artery (HARRA) Study

Circ Cardiovasc IntervPublished single-center randomized controlled trial

Authors' conclusion

The LRA was associated with significantly less cumulative and normalized radiation exposure to the thorax, abdomen, left eye, and right eye of the primary operator compared with HARRA during diagnostic cardiac catheterization. Operators should consider using LRA more frequently than HARRA for diagnostic cardiac catheterization as this approach can reduce occupational radiation exposure.

Study context

Population
Patients undergoing diagnostic cardiac catheterization; radiation exposure of the primary operatorpatients randomized
Participants
534 patients
Comparison
Left radial artery (LRA) approach compared with a uniform hyper-adducted right radial artery (HARRA) approach
  • LRAn = 269
  • HARRAn = 265

Primary result

As reported in the abstract

Cumulative radiation, thorax

P < 0.001

Further findings

Cumulative radiation, abdomen

P < 0.001

Cumulative radiation, left eye

P < 0.001

Cumulative radiation, right eye

P = 0.01

Subclavian tortuosity · lower with LRA

P < 0.001

OutcomeLRAHARRAP value
Normalized radiation, thorax0.38 ± 0.350.49 ± 0.24P < 0.001
Normalized radiation, abdomen1.06 ± 0.721.38 ± 0.69P < 0.001
Normalized radiation, left eye0.10 ± 0.090.15 ± 0.10P < 0.001
Normalized radiation, right eye0.04 ± 0.060.05 ± 0.06P = 0.02

Original publication

Operator Radiation Exposure Comparing the Left Radial Artery Approach and a Uniform Hyper-Adducted Right Radial Artery Approach: The HARRA Study. Circ Cardiovasc Interv. Published 19 March 2025. doi:10.1161/circinterventions.124.014602

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