Arrhythmias & electrophysiology
Health economic evaluation of nation-wide screening programmes for atrial fibrillation in the Netherlands
Authors' conclusion
Most single-time point AF screening strategies are cost-saving and have an important impact on stroke prevention.
Study context
- Population
- Netherlands; model inputs from ARISTOTLE, RE-LY and ROCKET atrial fibrillation (AF) trials and Dutch observational dataper 100,000 people screened
- Comparison
- AF screening programmes vs no screening
- Outcome
- Impact and cost-effectiveness of AF screening programmes
Methodological detailsMarkov model cost-effectiveness analysis, societal perspective, univariate, probabilistic sensitivity and scenario analyses
- Markov model cost-effectiveness analysis
- Societal perspective
- Univariate, probabilistic sensitivity and scenario analyses
Main finding
As reported in the abstract
Gain in QALYs per 100 000 screened, by strategy
984 to 8727
Mean cost difference per 100 000 screened, by strategy
−6650 000€ to 898 000€
Likelihood screening all patients ≥75 years at geriatric outpatient clinic was cost-saving (probabilistic sensitivity analysis (PSA))
100%
Strategies cost-saving in ≥74% of PSA simulations
4 of 6
Further findings
Newly detected AF patients in the Netherlands (maximum), by strategy
- Maximum newly detected AF patients
- 4554 to 39 270
Strokes prevented with adequate anticoagulation (single-time point screening)
- Maximum strokes prevented
- >3000
- Opportunistic screening of all patients ≥65 years at GP office had the highest impact on strokes prevented among cost-saving strategies
Original publication
Health economic evaluation of nation-wide screening programmes for atrial fibrillation in the Netherlands. Eur Heart J Qual Care Clin Outcomes. Published 26 July 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →