Valvular & structural heart disease
Health Status After Transcatheter Tricuspid-Valve Repair in Patients With Severe Tricuspid Regurgitation
Authors' conclusion
T-TEER with the TriClip system resulted in substantial and sustained health status improvement in patients with severe TR compared with medical therapy alone.
Study context
- Population
- Patients with severe tricuspid regurgitation
- Participants
- 175 vs 175
- Comparison
- Tricuspid transcatheter edge-to-edge repair (T-TEER) vs medical therapy
- T-TEERn = 175
- Medical therapyn = 175reference
- Primary endpoint
- Health status by KCCQ overall summary score (range 0-100; higher = better)
- Follow-up
- 1 month and 1 year
Primary result
As reported in the abstract
KCCQ overall summary score
T-TEER vs Medical therapyMean between-group difference, points (95% CI)
1 month
9.4(5.3–13.4)
1 year
10.4(6.3–14.6)
Further findings
Alive and well (KCCQ overall summary ≥60 and no decline >10 points from baseline) · 1 year · NNT 3.5
P < 0.001
Kansas City Cardiomyopathy Questionnaire (KCCQ) benefit by baseline KCCQ overall summary score
- Benefit of T-TEER diminished as baseline KCCQ overall summary score increased
- Pint < 0.001
Exploratory analyses
- Much of the health status benefit explained by tricuspid regurgitation (TR) reduction; health status improvement strongly correlated with reduced 1-year mortality and HF hospitalization
- Exploratory
Original publication
Health Status After Transcatheter Tricuspid-Valve Repair in Patients With Severe Tricuspid Regurgitation. J Am Coll Cardiol. Published 26 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →