Aortic & peripheral vascular disease
Health status and cognitive function for risk stratification in chronic coronary and peripheral artery disease
Authors' conclusion
Adding health status and cognitive functioning information to biomedical evaluations can augment cardiovascular risk-stratification in CAD and PAD.
Study context
- Population
- Stable coronary artery disease (CAD) and peripheral artery disease (PAD) patients from the COMPASS trial
- Participants
- 23,433 vs 6,899
- Comparison
- Higher vs lower EQ visual analogue scale (VAS) health status and Digit Symbol Substitution test (DSST) cognitive function scores
- CADn = 23,433
- PADn = 6,899
- Primary endpoint
- Incident MACE, and combined MACE or major adverse limb events
Methodological detailsinternational, multi-centre, fully adjusted hierarchical Cox regression
- International
- Multi-centre
- Fully adjusted hierarchical Cox regression
Primary result
As reported in the abstract
MACE or major adverse limb events
Hazard ratio (95% CI)
CADEQ VAS, per 10 unit increase
0.89(0.88–0.89)
PADEQ VAS, per 10 unit increase
0.89(0.88–0.89)
CADDSST, per 5 unit increase
0.95(0.94–0.95)
PADDSST, per 5 unit increase
0.95(0.94–0.95)
Each row per its own increment, as printed
Further findings
Population attributable risk, lower two vs upper quartiles
EQ-5D
DSST
Original publication
Health status and cognitive function for risk stratification in chronic coronary and peripheral artery disease. Eur J Prev Cardiol. Published 29 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →