Healthy sleep score changes and incident cardiovascular disease in European prospective community-based cohorts
Authors' conclusion
Higher HSS and HSS improvement over time are associated with a lower risk of CHD and stroke in the community.
Study context
- Population
- CVD-free community adults aged 53–64 years, Paris (France) and Lausanne (Switzerland)44.6% women
- Participants
- 11,347 adults
- Exposure
- Per 1-point increment in healthy sleep score
- Outcome
- Incident CVD events:
- CHD
- Stroke
- Follow-up
- Median 8.9 years
Methodological detailspooled analysis of 2 community-based cohorts (Paris Prospective Study III, CoLaus|PsyCoLaus)
- Pooled analysis of 2 community-based cohorts (Paris Prospective Study III, CoLaus|PsyCoLaus)
Main finding
As reported in the abstract
Incident CVD per 1-point increment in baseline HSS · median 8.9 years (IQR 8.0-10.0)
First CVD events (339 coronary heart disease (CHD), 175 stroke)
499
HR for CVD per 1-point healthy sleep score (HSS) increment (risk decreased by 18%)
0.82
95% CI 0.76–0.89
Observational data: associations, not effects.
Further findings
Incident CVD per unit higher follow-up HSS (over 2-5 years) · median 6.0 years (IQR 4.0-8.0) after second follow-up
- First CVD events (194 CHD, 72 stroke)
- 262
- HR for CVD per unit higher follow-up HSS (risk decreased by 16%)
- 0.84 (95% CI 0.73-0.97)
- Adjusted for baseline HSS and covariates
Original publication
Healthy sleep score changes and incident cardiovascular disease in European prospective community-based cohorts. Eur Heart J. Published 20 October 2023. doi:10. 1093/ eurheartj/ ehad657
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