Coronary disease & ACS

Healthy sleep score changes and incident cardiovascular disease in European prospective community-based cohorts

Eur Heart JPublished Prospective cohort study

Authors' conclusion

Higher HSS and HSS improvement over time are associated with a lower risk of CHD and stroke in the community.

Study context

Population
CVD-free community adults aged 53–64 years, Paris (France) and Lausanne (Switzerland)44.6% women
Participants
11,347 adults
Exposure
Per 1-point increment in healthy sleep score
Outcome
Incident CVD events:
  • CHD
  • Stroke
Follow-up
Median 8.9 years
Methodological detailspooled analysis of 2 community-based cohorts (Paris Prospective Study III, CoLaus|PsyCoLaus)
  • Pooled analysis of 2 community-based cohorts (Paris Prospective Study III, CoLaus|PsyCoLaus)

Main finding

As reported in the abstract

Incident CVD per 1-point increment in baseline HSS · median 8.9 years (IQR 8.0-10.0)

First CVD events (339 coronary heart disease (CHD), 175 stroke)

499

HR for CVD per 1-point healthy sleep score (HSS) increment (risk decreased by 18%)

0.82

95% CI 0.76–0.89

Observational data: associations, not effects.

Further findings

Incident CVD per unit higher follow-up HSS (over 2-5 years) · median 6.0 years (IQR 4.0-8.0) after second follow-up

First CVD events (194 CHD, 72 stroke)
262
HR for CVD per unit higher follow-up HSS (risk decreased by 16%)
0.84 (95% CI 0.73-0.97)
  • Adjusted for baseline HSS and covariates

Original publication

Healthy sleep score changes and incident cardiovascular disease in European prospective community-based cohorts. Eur Heart J. Published 20 October 2023. doi:10.1093/eurheartj/ehad657

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