Arrhythmias & electrophysiology
Heart Failure Events After Long-term Continuous Screening for Atrial Fibrillation: Results From the Randomized LOOP Study
Authors' conclusion
In an older population with additional stroke risk factors, ILR screening for atrial fibrillation tended to be associated with a lower rate of total HF events and cardiovascular death, particularly those related to HFrEF.
Study context
- Population
- Older individuals with additional stroke risk factors
- Participants
- 6,004 individuals
- Comparison
- Implantable loop recorder (ILR) screening for AF vs usual care
- ILRn = 1,501
- Controln = 4,503reference
- Primary endpoint
- HF event or CV death
Primary result
As reported in the abstract
ILR vs ControlHazard ratio (95% CI)
Time-to-first event
0.78(0.61–1.01)
Total events (Andersen-Gill)
0.77(0.59–1.01)
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| HFrEF event or CV death, total events | 0.74 (0.56–0.98) | |
| HFrEF event, total events | 0.65 (0.44–0.97) | |
| 0.512Hazard ratio (log scale) |
Heart failure (HF) event
- Similar results to primary outcome
Original publication
Heart Failure Events After Long-term Continuous Screening for Atrial Fibrillation: Results From the Randomized LOOP Study. Circ Arrhythm Electrophysiol. Published 18 July 2024. doi:10.
Summarised from the published abstract; every number is checked against it