Arrhythmias & electrophysiology
Left Atrial Strain Predicts Subclinical Atrial Fibrillation Detected by Long-term Continuous Monitoring in Elderly High-Risk Individuals
Primary result · SCAFResult — go to the resultHazard ratio 1.04 CI 1.02–1.05Authors' conclusion
LA reservoir and contraction strain are independent predictors of SCAF in elderly at risk of stroke. This also applies to individuals with normal LA size and diastolic function.
Study context
- Population
- Elderly at risk of stroke who received a loop recorder (Reveal LINQ) in the LOOP study278 (29%) with subclinical atrial fibrillation (SCAF)
- Participants
- 956 elderly
- Comparison
- Low vs high left atrial (LA) strain for prediction of SCAF
- Primary endpoint
- SCAF (≥6 minutes) detected by continuous rhythm monitoring
- Follow-up
- Median monitoring 35 months (IQR, 20-40 months)
Methodological detailsechocardiographic substudy, Cox proportional hazards regression adjusted for AF risk factors
- Echocardiographic substudy
- Cox proportional hazards regression adjusted for AF risk factors
Primary result
SCAF
Hazard ratio
1.04
CI 1.02–1.05
By group
LA reservoir strain
HR 1.04 (CI 1.02–1.05)
Per 1% decrease, as printed
As reported in the abstract
Further findings
Competing risk analyses; participants with normal LA size and diastolic function (subgroup)
- Findings unchanged
Original publication
Left Atrial Strain Predicts Subclinical Atrial Fibrillation Detected by Long-term Continuous Monitoring in Elderly High-Risk Individuals. Circ Cardiovasc Imaging. Published 5 March 2024. doi:10.
Summarised from the published abstract; every number is checked against it