Valvular & structural heart disease
Heart Failure Hospitalizations and Clinical Outcomes in Patients Undergoing Tricuspid Transcatheter Edge-To-Edge Repair: Insights from EuroTR
Authors' conclusion
In the EuroTR cohort, a history of HFH was highly prevalent and associated with worse clinical outcomes. Among high-risk patients with symptomatic TR, T-TEER significantly lowered HFH risk, with residual TR grade ≤2 being the key predictor for reduced HFH incidence.
Study context
- Population
- Patients undergoing tricuspid transcatheter edge-to-edge repair (T-TEER) for symptomatic tricuspid regurgitation (TR), EuroTR registryEuroTR registry
- Participants
- 1,000 patients
- Exposure
- Prior heart failure hospitalization (HFH) vs no HFH in the year before T-TEER
- No HFHn = 361reference
- Single HFHn = 459
- Multiple HFHn = 180
Methodological detailsreal-world, multivariable analysis
- Real-world
- Multivariable analysis
Main finding
As reported in the abstract
Prevalence of HFH the year before T-TEER and mortality
Each group vs no HFHAdjusted hazard ratio (95% CI)
Single HFH
1.51(1.11–2.06)
Multiple HFH
1.63(1.15–2.31)
Observational data: associations, not effects.
Further findings
HFH risk after vs before T-TEER · 1 year following T-TEER
- HFH risk decreased vs the previous year
- 72%
Procedural success (residual TR ≤2)
- Did not differ between single, multiple or no HFH
- Sole independent predictor for reducing HFHs
All-cause mortality or HFH
- Higher risk with a history of HFH
Original publication
Heart Failure Hospitalizations and Clinical Outcomes in Patients Undergoing Tricuspid Transcatheter Edge-To-Edge Repair: Insights from EuroTR. Eur J Heart Fail. Published 18 July 2025. doi:10.
Summarised from the published abstract; every number is checked against it