Arrhythmias & electrophysiology

Heart rate and death and hospitalization for heart failure in patients with persistent or permanent atrial fibrillation: Insights from the ARISTOTLE trial

Am Heart JPublished Secondary analysis of the ARISTOTLE randomised trial

Authors' conclusion

In patients with persistent or permanent AF, a faster heart rate is associated with a modest, but statistically significant increase in death and heart failure hospitalizations.

Study context

Population
Patients with persistent or permanent atrial fibrillation (AF)
Methodological detailsrandomized, double-blind
  • Randomized
  • Double-blind

Primary result

As reported in the abstract

Death and HF hospitalization by heart rate
  • Faster heart rate associated with a modest but statistically significant increase in death and HF hospitalizations

Original publication

Heart rate and death and hospitalization for heart failure in patients with persistent or permanent atrial fibrillation: Insights from the ARISTOTLE trial. Am Heart J. Published 26 July 2023. doi:10.1016/j.ahj.2023.07.006

Summarised from the published abstract; every number is checked against it

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