Valvular & structural heart disease
High-risk admission prior to transcatheter aortic valve replacement and subsequent outcomes
Main finding · All-cause deathResult — go to the resultAdjusted hazard ratio 1.29 95% CI 1.01–1.64Authors' conclusion
A hospitalization for heart failure, myocardial infarction, or syncope prior to TAVR was associated with a poorer prognosis
Study context
- Population
- All Danish patients undergoing transcatheter aortic valve replacement (TAVR), 2014–2021
- Participants
- 5,851 patients
- Exposure
- Preceding high-risk event vs none
- Preceding eventn = 759
- Outcome
- All-cause death
- Follow-up
- 1 year
Methodological detailsnationwide
- Nationwide
Main finding
As reported in the abstract
Adjusted hazard ratio
1.29
95% CI 1.01–1.64
By group
Preceding eventvs No preceding event
aHR 1.29 (95% CI 1.01–1.64)
Observational data: associations, not effects.
Further findings
| Outcome | Preceding event | No preceding event | aHR (95% CI) | |
|---|---|---|---|---|
| CV rehospitalization · 1 year | 15.0% | 8.2% | 1.60 (1.29–1.99) | |
| All-cause rehospitalization · 1 year | 57.6% | 50.6% | 1.08 (0.87–1.20) | |
| 0.512Adjusted hazard ratio (log scale) |
- Death, preceding HF admission (subgroup): Preceding HF admission 13.5% (95% CI 10.5%–16.5%)
- Death, preceding HF admission (subgroup): most common preceding event: HF hospitalization (n = 524)
Original publication
High-risk admission prior to transcatheter aortic valve replacement and subsequent outcomes. Am Heart J. Published 14 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →