Hospitalization for cardiovascular disease in the year after delivery of twin pregnancies
Authors' conclusion
Compared with singletons without HDP, twin pregnancies, even in the absence of HDP, are associated with increased risks for CVD complications in the first year post-partum.
Study context
- Population
- Delivery hospitalizations, US Nationwide Readmissions Database, 2010–2020
- Participants
- 36 million delivery hospitalizations
- Exposure
- Twin vs singleton deliveries, with and without hypertensive disease of pregnancy (HDP)
- Outcome
- CVD readmission
- Follow-up
- Within the year following delivery
Methodological detailsnationwide database
- Nationwide database
Main finding
As reported in the abstract
CVD readmission · first year post-partum
Each group vs singletons without HDPAdjusted hazard ratio (95% CI)
Twins with HDP
8.21(7.48–9.01)
Singletons with HDP
5.89(5.70–6.08)
Twins without HDP
1.95(1.75–2.17)
- Cardiovascular disease (CVD) readmission rate, twin pregnancies
- 1105.4 per 100 000 delivery admissions
- CVD readmission rate, singleton pregnancies
- 734.1 per 100 000 delivery admissions
Observational data: associations, not effects.
Original publication
Hospitalization for cardiovascular disease in the year after delivery of twin pregnancies. Eur Heart J. Published 3 February 2025. doi:10.
Summarised from the published abstract; every number is checked against it