Coronary disease & ACSCohort study
Hypertensive Disorders of Pregnancy Increase the Risk for Myocardial Infarction
- Population-based cohort study
- age-matched control subjects
Authors' conclusion
A history of HDP is associated with CAD earlier in life and with a future risk for myocardial infarction with both obstructive and nonobstructive coronary arteries.
Study context
- Population
- Parous women with incident coronary artery disease (CAD) who underwent coronary angiography, Olmsted County, Minnesota (USA), 2002–2016
- Participants
- 506 women
- Exposure
- History of HDP vs normotensive pregnancies
Main finding
As reported in the abstract
Higher SYNTAX score and MINOCA, HDP vs normotensive pregnancies
HDP vs NormotensiveOdds ratio (95% CI)P value
higher SYNTAX score
2.28(1.02–5.12)
P = 0.046MINOCA
2.08(1.02–4.25)
P = 0.044Observational data: associations, not effects.
Further findings
Age at CAD event
P = 0.030
Acute coronary syndrome (ACS)
- Strong association between HDP and ACS
- unadjusted P = 0.018
Original publication
Hypertensive Disorders of Pregnancy Increase the Risk for Myocardial Infarction. J Am Coll Cardiol. Published 6 November 2024. doi:10.1016/j.jacc.2024.06.049
Summarised from the published abstract; every number is checked against it