Heart failure & cardiomyopathies

Impact of congestion and perfusion status in the emergency department on severity of decompensation and short-term prognosis in patients with acute heart failure

Eur Heart J Acute Cardiovasc CarePublished Registry-based cohort study

Authors' conclusion

The presence of congestion/hypoperfusion at ED arrival is a simple clinical marker associated with a higher risk of severity/adverse short-term outcomes.

Study context

Population
Patients with acute HF in the emergency department (ED) (EAHFE Registry); median age 83 years, women 55.7%analysed
Participants
18,120 patients
Exposure
Severity of congestion/hypoperfusion at ED arrival
Outcome
Need for hospitalization, in-hospital all-cause mortality (hospitalized) and prolonged hospitalization (discharged alive)

Main finding

As reported in the abstract

>2 signs/symptoms of congestion
72%
≥1 sign/symptom of hypoperfusion
18%
Hospitalized
75%
In-hospital death
9%
Prolonged hospitalization (discharged alive)
47%
More congestion signs: hospitalization
P < 0.001
More congestion signs: prolonged stay
P = 0.011
More congestion signs: mortality (not significant)
P = 0.06
More hypoperfusion signs: hospitalization
P < 0.001
More hypoperfusion signs: mortality
P < 0.001
More hypoperfusion signs: prolonged stay (not significant)
P = 0.227

Observational data: associations, not effects.

Original publication

Impact of congestion and perfusion status in the emergency department on severity of decompensation and short-term prognosis in patients with acute heart failure. Eur Heart J Acute Cardiovasc Care. Published 22 September 2022. doi:10.1093/ehjacc/zuac115

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