Prevention & lipids

Impact of Nonalcoholic Hepatic Steatosis on the Warranty Period of a Coronary Artery Calcium Score of 0: Results From the Multi-Ethnic Study of Atherosclerosis

Circ Cardiovasc ImagingPublished Prospective cohort study

Main finding · New CAC incidence (CAC score >0)Result — go to the resultHazard ratio 1.28 95% CI 1.05–1.57

Authors' conclusion

Nonalcoholic hepatic steatosis had an impact on the warranty period of a CAC score of 0.

Study context

Population
MESA participants with baseline coronary artery calcium (CAC) score of 0 and ≥1 follow-up CT scan
Participants
1,944 participants
Exposure
Nonalcoholic hepatic steatosis vs no nonalcoholic hepatic steatosis
  • Nonalcoholic hepatic steatosisn = 268
Outcome
New CAC incidence (CAC score >0)

Main finding

As reported in the abstract

Hazard ratio

1.28

95% CI 1.05–1.57

P = 0.015

Nonalcoholic hepatic steatosisvs No nonalcoholic hepatic steatosis
HR 1.28 (95% CI 1.05–1.57); P = 0.015

Observational data: associations, not effects.

Further findings

Warranty period of CAC score of 0 (25% testing yield)

Warranty period of CAC score of 0 (25% testing yield)

Association consistent regardless of sex, race/ethnicity, age and 10-year atherosclerotic CVD risk

Original publication

Impact of Nonalcoholic Hepatic Steatosis on the Warranty Period of a Coronary Artery Calcium Score of 0: Results From the Multi-Ethnic Study of Atherosclerosis. Circ Cardiovasc Imaging. Published 17 September 2024. doi:10.1161/circimaging.123.016465

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