Heart failure & cardiomyopathies
Impact of Age on Characteristics, Performance Measures and Outcomes of Inpatients for Heart Failure in Beijing, China
Authors' conclusion
HF patients aged ≥75 years had distinct clinical profiles, received worse in-hospital therapies and experienced higher in-hospital and 1 year mortality.
Study context
- Population
- Heart failure (HF) inpatients admitted to five tertiary and four secondary hospitals of the Capital Medical University, Beijing, China
- Participants
- 1,244 vs 1,419
- Exposure
- HF inpatients aged ≥75 years vs <75 years
- ≥75 yearsn = 1,244
- <75 yearsn = 1,419reference
- Outcome
- Age-related differences in performance measures and in-hospital and 1-year mortality
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Mortality, older (≥75 years) vs younger (<75 years) patients
In-hospital mortality, older vs younger
2.7% vs. 1.3%
P = 0.011
1-year mortality, older vs younger
21.7% vs. 12.5%
P < 0.001
Observational data: associations, not effects.
Further findings
LVEF assessment, younger vs older
- LVEF assessed, younger vs older
- 81.7% vs. 80.5%, P = 0.426
BNP/NT-proBNP testing, younger vs older
- BNP/NT-proBNP tested, younger vs older (lower in younger)
- 84.8% vs. 89%, P = 0.001
Discharge therapy in HFrEF, older vs younger
- Beta-blockers, older vs younger
- 49.74% vs. 63.2%, P = 0.002
- ACEi/ARB, older vs younger
- 52.9% vs. 64.7%, P = 0.006
- Beta-blocker + ACEi/ARB, older vs younger
- 28.57% vs. 45.5%, P < 0.001
- MRA, older vs younger (equally likely)
- 80.8% vs. 84.1%, P = 0.322
Predictors of mortality
- Higher BMI associated with better outcomes in both age groups
- NYHA class IV and eGFR < 60 mL/min/1.73 m² independent predictors of 1-year mortality
- Associations between characteristics and mortality not modified by age
Original publication
Impact of Age on Characteristics, Performance Measures and Outcomes of Inpatients for Heart Failure in Beijing, China. ESC Heart Fail. Published 1 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →