Arrhythmias & electrophysiology

Impact of Age on Subcutaneous Implantable Cardioverter-Defibrillator in a Large Patient Cohort: Mid-Term Follow-Up

JACC Clin ElectrophysiolPublished Prospective cohort study

Authors' conclusion

Implant complications and appropriate and inappropriate shock rates were similar among age groups. S-ICD for secondary prevention was more common in the young group. Replacing a TV-ICD for an S-ICD increases with age.

Study context

Population
Patients with a subcutaneous ICD (subcutaneous implantable cardioverter-defibrillator (S-ICD)) in the S-ICD post-approval study
Participants
1,637 patients
Exposure
S-ICD outcomes by age group: young vs adult vs elderly
Outcome
Clinical outcomes by age group
Follow-up
3 years after implantation
Methodological detailsmulticenter, post-approval study
  • Multicenter
  • Post-approval study

Main finding

As reported in the abstract

Mortality

Complications

Appropriate shock

Inappropriate shock

Mortality significantly higher in elderly
P < 0.0001
Appropriate shock did not differ between groups
P = 0.96
Inappropriate shock did not differ between groups
P = 0.98

Observational data: associations, not effects.

Further findings

S-ICD as replacement of a TV-ICD

Secondary prevention indication

Safety

Complications · 3 years of follow up after implantation

Inappropriate shock · 3 years of follow up after implantation

Inappropriate shock — Did not differ between groups
P = 0.98

Complications · 3 years of follow up after implantation

Did not differ significantly

Original publication

Impact of Age on Subcutaneous Implantable Cardioverter-Defibrillator in a Large Patient Cohort: Mid-Term Follow-Up. JACC Clin Electrophysiol. Published 6 September 2023. doi:10.1016/j.jacep.2023.06.013

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