Arrhythmias & electrophysiology
Impact of Age on Subcutaneous Implantable Cardioverter-Defibrillator in a Large Patient Cohort: Mid-Term Follow-Up
Authors' conclusion
Implant complications and appropriate and inappropriate shock rates were similar among age groups. S-ICD for secondary prevention was more common in the young group. Replacing a TV-ICD for an S-ICD increases with age.
Study context
- Population
- Patients with a subcutaneous ICD (subcutaneous implantable cardioverter-defibrillator (S-ICD)) in the S-ICD post-approval study
- Participants
- 1,637 patients
- Exposure
- S-ICD outcomes by age group: young vs adult vs elderly
- Outcome
- Clinical outcomes by age group
- Follow-up
- 3 years after implantation
Methodological detailsmulticenter, post-approval study
- Multicenter
- Post-approval study
Main finding
As reported in the abstract
Mortality
Complications
Appropriate shock
Inappropriate shock
- Mortality significantly higher in elderly
- P < 0.0001
- Appropriate shock did not differ between groups
- P = 0.96
- Inappropriate shock did not differ between groups
- P = 0.98
Observational data: associations, not effects.
Further findings
S-ICD as replacement of a TV-ICD
Secondary prevention indication
Safety
Complications · 3 years of follow up after implantation
Inappropriate shock · 3 years of follow up after implantation
- Inappropriate shock — Did not differ between groups
- P = 0.98
Complications · 3 years of follow up after implantation
- Did not differ significantly
Original publication
Impact of Age on Subcutaneous Implantable Cardioverter-Defibrillator in a Large Patient Cohort: Mid-Term Follow-Up. JACC Clin Electrophysiol. Published 6 September 2023. doi:10. 1016/ j. jacep. 2023. 06. 013
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