Heart failure & cardiomyopathies
Impact of Atrial Fibrillation on Cerebro-Cardiovascular Outcome of Heart Failure with Mildly-Reduced Ejection Fraction
Authors' conclusion
AF is independently associated with an increased risk of CCE in HFmrEF patients within 1 year and at a mean of 33 months after discharge.
Study context
- Population
- Hospitalised patients with heart failure (HF) with mildly-reduced EF (heart failure with mildly-reduced ejection fraction (HFmrEF))matched: 296 atrial fibrillation (AF), 592 non-AF
- Participants
- 1,691 patients
- Exposure
- AF vs non-AF in HFmrEF
- AFn = 296
- Non-AFn = 592reference
- Outcome
- Cerebro-cardiovascular events:
- CCE: HF rehospitalisation
- Stroke
- CV death
- Follow-up
- 1 year and mean 33 months after discharge
Methodological detailspropensity-score matched, consecutive patients, Follow-up by telephone interview, clinical visit or community visit
- Propensity-score matched
- Consecutive patients
- Follow-up by telephone interview, clinical visit or community visit
Main finding
As reported in the abstract
CCE · 1 year and mean 33 months
AF
- Cerebro-cardiovascular events (CCE) at 1 year
- 59.1%
- CCE at mean 33 months
- 77.0%
Non-AF
- CCE at 1 year
- 48.5%
- CCE at mean 33 months
- 70.6%
Cerebro-cardiovascular events (CCE) at 1 year
AF59.1%
Non-AF48.5%
CCE at mean 33 months
AF77.0%
Non-AF70.6%
AF vs Non-AFHazard ratio (95% CI)P value
Adjusted; within 1 year
1.31(1.07–1.61)
P = 0.010Adjusted; 33 months
1.20(1.00–1.43)
P = 0.050Observational data: associations, not effects.
Original publication
Impact of Atrial Fibrillation on Cerebro-Cardiovascular Outcome of Heart Failure with Mildly-Reduced Ejection Fraction. ESC Heart Fail. Published 8 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →