Impact of biomarker type on periprocedural myocardial infarction in patients undergoing elective percutaneous coronary intervention (PCI)
Authors' conclusion
In the setting of elective PCI, using hs-cTn instead of CK-MB resulted in a substantial increase in SCAI periprocedural MI events, which were not prognostically relevant in the absence of concurrent CK-MB elevations.
Study context
- Population
- Patients undergoing elective PCI, 2017–2021
- Participants
- 1,010 patients
- Exposure
- Society for Cardiovascular Angiography and Interventions (SCAI) periprocedural myocardial infarction (MI) by CK-MB vs hs-cTnI
- Outcome
- All-cause death
- Follow-up
- 1-year follow-up
Main finding
As reported in the abstract
All-cause death associated with periprocedural MI · 1 year
Adjusted hazard ratio (95% CI)P value
CK-MBperiprocedural MI by CK-MB
4.27(1.23–14.8)
P = 0.022hs-cTnIperiprocedural MI by hs-cTnI
2.04(0.94–4.45)
P = 0.072hs-cTnIhs-cTnI periprocedural MI accompanied by CK-MB criteria
4.64(1.32–16.31)
P = 0.017Observational data: associations, not effects.
Further findings
Incidence of SCAI periprocedural MI
Ancillary criteria (angiographic, ECG, cardiac imaging)
- hs-cTnI periprocedural MI without CK-MB criteria associated with lower rates of ancillary criteria
Original publication
Impact of biomarker type on periprocedural myocardial infarction in patients undergoing elective PCI. Eur Heart J Qual Care Clin Outcomes. Published 17 November 2022. doi:10.
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