Valvular & structural heart disease
Impact of early changes in cardiac damage following transcatheter aortic valve implantation
Authors' conclusion
Cardiac deterioration within 30 days is associated with poor clinical prognosis.
Study context
- Population
- Aortic stenosis (AS) patients undergoing transcatheter aortic valve implantation (TAVI), classified into cardiac damage stages 0–4
- Participants
- 644 patients
- Exposure
- Change in cardiac damage stage within 30 days post-TAVI
- Outcome
- Mortality
- Follow-up
- 2 years
Methodological detailsconsecutive enrolment
- Consecutive enrolment
Main finding
As reported in the abstract
2-year mortality
Further cardiac damage vs UnchangedHazard ratio (95% CI)P value
Crude
22.04(9.87–49.20)
P < 0.001Independent risk factor
19.564(8.047–47.565)
P < 0.001- Residual cardiac damage within 30 days post-TAVI associated with 2-year mortality (HR 2.97, 95% CI 2.07-4.25)
- P < 0.001
Observational data: associations, not effects.
Further findings
Change in cardiac damage stage within 30 days
- Baseline stage changed
- 22.2%
- Accompanied by improvements in dyspnoea and left ventricular ejection fraction (LVEF)
Original publication
Impact of early changes in cardiac damage following transcatheter aortic valve implantation. EuroIntervention. Published 19 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →