Heart failure & cardiomyopathies
Impact of Frailty and Delirium Among Older Adults Admitted With Acute Decompensated Heart Failure
Authors' conclusion
Frailty and delirium, independently and in combination, led to higher odds of in-hospital mortality and nonhome disposition at discharge among patients hospitalized with ADHF.
Study context
- Population
- Patients ≥65 years hospitalised with acute decompensated HF (preserved or reduced LVEF), US, 2016–2018
- Participants
- 3,577,433 weighted hospitalizations
- Exposure
- Delirium and frailty risk categories vs no delirium and low frailty risk
- Outcome
- In-hospital mortality and nonhome discharge
Methodological detailsNationwide Inpatient Sample 2016–2018, multivariable logistic regression
- Nationwide Inpatient Sample 2016–2018
- Multivariable logistic regression
Main finding
As reported in the abstract
Each group vs no delirium, low frailty riskOdds ratio (95% CI)
Deliriumin-hospital mortality
3.74(3.70–3.78)
Moderate frailty riskin-hospital mortality
4.02(3.96–4.09)
High frailty riskin-hospital mortality
8.63(8.47–8.78)
Deliriumnonhome discharge
4.21(4.18–4.25)
Moderate frailty risknonhome discharge
2.95(2.94–2.97)
High frailty risknonhome discharge
8.86(8.78–8.94)
Delirium + high frailty riskin-hospital mortality; highest of combinations
12.18(11.89–12.48)
Delirium + high frailty risknonhome discharge; highest of combinations
14.01(13.77–14.26)
Observational data: associations, not effects.
Original publication
Impact of Frailty and Delirium Among Older Adults Admitted With Acute Decompensated Heart Failure. JACC Adv. Published 20 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →