Cardio-oncology & other

Impact of hospital lead extraction volume on management of cardiac implantable electronic device-associated infective endocarditis

EuropacePublished Retrospective cohort study

Main finding · TLE performed during admissionResult — go to the resultAdjusted odds ratio 4.26 95% CI 3.53–5.15

Authors' conclusion

Admissions to high-volume TLE centres were associated with higher utilization of TLE for management of CIED-associated IE.

Study context

Population
Admissions for patients with cardiac implantable electronic device (CIEDs) hospitalised with infective endocarditis (IE) at transvenous lead extraction/removal (TLE) centres, 2016–2019
Participants
21,545 admissions
Exposure
High- and medium-volume vs low-volume TLE centres
Outcome
TLE utilization
Methodological detailsNationwide Readmissions Database
  • Nationwide Readmissions Database

Main finding

TLE performed during admission

Adjusted odds ratio

4.26

95% CI 3.53–5.15

By group

Low-volume

6.9

%

Medium-volume

19.3

%

High-volume

26%

High-volume vs Low-volume
adjusted OR 4.26 (95% CI 3.53–5.15)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Inpatient mortality

Similar across low-, medium- and high-volume centres

Safety

TLE-associated complications

  • TLE-associated complications: P = 0.493

Original publication

Impact of hospital lead extraction volume on management of cardiac implantable electronic device-associated infective endocarditis. Europace. Published 27 December 2024. doi:10.1093/europace/euae308

Summarised from the published abstract; every number is checked against it

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