Arrhythmias & electrophysiologyResearch article
Impact of Interelectrode Spacing on Ventricular Tachycardia Substrate Mapping
- retrospectively analyzed
Authors' conclusion
Widely spaced bipolar electrograms may provide complementary functional information beyond that obtained with conventional near-field recordings by incorporating broader-field electrical components, thereby offering additional insight into the potential 3-dimensional characteristics of the arrhythmogenic substrate.
Study context
- Population
- Patients undergoing catheter ablation for scar-related ventricular tachycardia (VT)
- Participants
- 35 Sixty-eight high-density substrate maps
- Comparison
- WEM compared with CEM
Main finding
As reported in the abstract
Bipolar amplitudes, multicomponent electrograms, split potentials
WEM demonstrated higher bipolar amplitudes, a greater prevalence of multicomponent electrograms, and a lower prevalence of split potentials
all P < 0.01
Further findings
Activation gaps
- Activation gaps: exploratory analysis of 6 VTs with evaluable activation maps
- Activation gaps: larger with closely than widely spaced bipolar mapping; P = 0.03
Lines of block delineated by split potentials on CEM
- frequently attenuated or no longer apparent on WEM
Diastolic or presystolic far-field potentials
- In 4 VTs, widely spaced recordings identified diastolic or presystolic far-field potentials not evident with closely spaced recordings
- 4
Original publication
Impact of Interelectrode Spacing on Ventricular Tachycardia Substrate Mapping. JACC Clin Electrophysiol. Published 24 September 2026. doi:10.1016/j.jacep.2026.08.021
Summarised from the published abstract; every number is checked against it