Arrhythmias & electrophysiology

Accuracy of non-invasive electrocardiographic imaging in scar-dependent ventricular tachycardia: relationship to arrhythmogenic substrate and imaging defined scar

EuropacePublished Diagnostic accuracy study

An erratum to this article was published (Europace, 2 Jun 2026 ↗)

Authors' conclusion

ECGi mapping with VIVO can accurately predict the arrhythmogenic substrate for scar-dependent VT.

Study context

Population
Patients with scar-dependent ventricular tachycardia (VT)
Participants
31 patients · 48 VTs
Comparison
Electrocardiographic imaging (ECGi) vs electro-anatomical mapping
Outcome
Accuracy of ECGi in localizing the arrhythmogenic substrate (VT exit site region concordance with EAM by AHA segment)
Methodological detailsblinded analysis
  • Blinded analysis

Performance

As reported in the abstract

VT-ESR match, ECGi vs EAM

Complete match (exact AHA segment concordance)

67%

Partial match (adjacent segments)

21%

Further findings

OutcomeECGiEAM
Epicardial VT-ESR identification
Sensitivity, ischaemic cardiomyopathy71.4%Not reported in the abstractEAM: not reported in the abstract
Specificity, ischaemic cardiomyopathy92.9%Not reported in the abstractEAM: not reported in the abstract
Sensitivity, non-ischaemic cardiomyopathy66.7%Not reported in the abstractEAM: not reported in the abstract
Specificity, non-ischaemic cardiomyopathy100%Not reported in the abstractEAM: not reported in the abstract

ECGi VT-exit site region (VT-ESR) relationship to scar, isthmus and successful ablation sites

ECGi VT-ESR within or adjacent to imaging-defined scar
85%
VT isthmus within or adjacent to ECGi VT-ESR
77%
Successful ablation sites within or adjacent to ECGi VT-ESR
82%
Accuracy not affected by cardiomyopathy type or VT cycle length

Original publication

Accuracy of non-invasive electrocardiographic imaging in scar-dependent ventricular tachycardia: relationship to arrhythmogenic substrate and imaging defined scar. Europace. Published 9 April 2026. doi:10.1093/europace/euag076

Summarised from the published abstract; every number is checked against it

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