Valvular & structural heart disease
Impact of Mitral Regurgitation Etiology on Mitral Surgery After Transcatheter Edge-to-Edge Repair: From the CUTTING-EDGE Registry
Authors' conclusion
The risk of MV surgery after TEER is nontrivial, with higher mortality after surgery, especially in SMR patients.
Study context
- Population
- Patients undergoing mitral valve (MV) surgery after failed transcatheter edge-to-edge repair (TEER), July 2009–July 202047% primary (PMR), 53.0% SMR
- Participants
- 330 patients
- Exposure
- SMR vs PMR in MV surgery after failed TEER
- Outcome
- MVARC outcomes
- Follow-up
- 30 days and 1 year
Methodological detailsCUTTING-EDGE registry, Median follow-up 9.1 months (IQR: 1.1-25.8 months) after surgery
- CUTTING-EDGE registry
- Median follow-up 9.1 months (IQR: 1.1-25.8 months) after surgery
Main finding
As reported in the abstract
Mortality
30-day mortality
P = 0.072
1-year mortality
P = 0.019
| Outcome | PMR | SMR |
|---|---|---|
| 30-day observed-to-expected mortality ratio | 2.6 (95% CI: 1.2-4.0) | 4.6 (95% CI: 2.6-6.6) |
- 30-day observed-to-expected mortality ratio, overall
- 3.6 (95% CI: 1.9-5.3)
Observational data: associations, not effects.
Further findings
Aborted TEER, surgery for mitral stenosis after TEER, MV repair
Aborted TEER
P = 0.043
Surgery for mitral stenosis
P = 0.008
MV repair
P = 0.019
Original publication
Impact of Mitral Regurgitation Etiology on Mitral Surgery After Transcatheter Edge-to-Edge Repair: From the CUTTING-EDGE Registry. JACC Cardiovasc Interv. Published 22 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →