Acute cardiac care & resuscitation
Impact of off-hours admissions in STEMI-related cardiogenic shock managed with microaxial flow pump - insights from J-PVAD
Main finding · Deaths during follow-up (median 22 days, IQR 13-38)Result — go to the resultAdjusted hazard ratio 1.60 95% CI 1.07–2.39Authors' conclusion
Our findings indicated the persistence of the "off-hours effect" in STEMI-CS patients treated with Impella.
Study context
- Population
- STEMI complicated by cardiogenic shock treated with Impella, Japanese registry (J-PVAD), Feb 2020–Dec 2021of 1,207 STEMI patients
- Participants
- 566 participants
- Exposure
- Off-hours vs on-hours admission
- On-hoursn = 300reference
- Outcome
- Mortality
- Follow-up
- 30 days
Methodological detailsregistry-based, consecutive patients
- Registry-based
- Consecutive patients
Main finding
As reported in the abstract
Deaths during follow-up (median 22 days, IQR 13-38)
Adjusted hazard ratio
1.60
95% CI 1.07–2.39
P = 0.02
Events by group
Off-hoursvs On-hours
aHR 1.60 (95% CI 1.07–2.39); P = 0.02
Observational data: associations, not effects.
Original publication
Impact of off-hours admissions in STEMI-related cardiogenic shock managed with microaxial flow pump - insights from J-PVAD. EuroIntervention. Published 19 August 2024. doi:10.
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