Acute cardiac care & resuscitation

Outcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units

JACC AdvPublished Retrospective cohort study

Main finding · In-hospital mortalityResult — go to the resultOdds ratio 0.85 95% CI 0.78–0.93

Authors' conclusion

Admission to the CICU, as compared to MICU, was associated with lower in-hospital mortality for patients with AMI.

Study context

Population
Patients with a primary diagnosis of acute myocardial infarction (AMI) requiring invasive mechanical ventilation, Vizient Clinical Data Base, October 2015–December 2019
Participants
12,639 patients
Exposure
CICU vs medical ICU (MICU) admission
  • CICUn = 9,454
  • MICUn = 3,185reference
Outcome
In-hospital mortality
Methodological detailsmultivariable logistic regression
  • Multivariable logistic regression

Main finding

As reported in the abstract

Odds ratio

0.85

95% CI 0.78–0.93

P = 0.001

By group

CICUvs MICU
OR 0.85 (95% CI 0.78–0.93); P = 0.001

Observational data: associations, not effects.

Further findings

Ventilator days · not statistically different after multivariable adjustment

P = 0.81

In-hospital mortality, stratified by cardiogenic shock, cardiac arrest, STEMI, largest hospital size (>750 beds), teaching hospitals (subgroups)

Lower in-hospital mortality with CICU persisted in all strata
all, P < 0.05

Original publication

Outcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units. JACC Adv. Published 14 August 2024. doi:10.1016/j.jacadv.2024.101199

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