Impact of prognostic nutritional index on mortality among patients receiving coronary artery bypass grafting surgery: a retrospective cohort study
Authors' conclusion
PNI at various time points may play a crucial predictive role in mortality among CABG-treated patients, and a low PNI serves as a risk factor for both short- and long-term survival.
Study context
- Population
- Patients who underwent isolated coronary artery bypass grafting (CABG)patients who underwent isolated CABG, 2825 discharged alive
- Participants
- 2,889 patients
- Exposure
- Higher vs lower Prognostic Nutritional Index (PNI) vs lower PNI)
- Outcome
- Short- and long-term mortality
- Follow-up
- Within 30 days (short-term); median 54.9 months (long-term)
Methodological detailsfour medical centres
- Four medical centres
Main finding
As reported in the abstract
Estimate (95% CI)P value
Higher preoperative PNIshort-term mortality; multivariate logistic regression
OR 0.852 per unit increase(0.802–0.904)
P < 0.001Normal PNI at discharge (>40)long-term all-cause mortality; multivariate Cox regression
HR 0.718(0.529–0.974)
P = 0.033Per unit increase, as printed
- Died within 30 days following CABG
- 64 (2.2%)
- Deaths among the 2825 patients discharged alive
- 199
- Higher long-term survival with normal PNI at discharge (>40) vs lower PNI (≤40)
- log-rank p=0.003
Observational data: associations, not effects.
Original publication
Impact of prognostic nutritional index on mortality among patients receiving coronary artery bypass grafting surgery: a retrospective cohort study. Heart. Published 11 February 2025. doi:10.
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