Valvular & structural heart disease
Impact of Severity and Extent of Iliofemoral Atherosclerosis on Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement (TAVR)
Authors' conclusion
The Hostile score proved useful in predicting non-puncture site vascular complications after TAVR.
Study context
- Population
- Patients undergoing transfemoral TAVR with contemporary devices, March 2014–June 2022 (SwissTAVI Registry)
- Participants
- 2,023 patients
- Exposure
- Hostile score for prediction of vascular complications after transfemoral TAVR
- Outcome
- Puncture and non-puncture site iliofemoral vascular complications (validity of Hostile score)
Methodological detailsvalidation of a risk score
- Validation of a risk score
Main finding
As reported in the abstract
Hostile score prediction of vascular complications
Vascular complications
1.00
median · IQR 0–5.00
No complications
1.00
median · IQR 0–4.00
P < 0.001
- Puncture site vascular complications
- 106 (5.2%)
- Non-puncture site vascular complications
- 28 (1.4%)
- AUC, puncture site vascular complications
- 0.554
- AUC, non-puncture site vascular complications
- 0.829
- Higher Hostile score, independent predictor of non-puncture site complications
- OR 1.91 (1.55-2.35) (95% CI)
Observational data: associations, not effects.
Further findings
Independent predictors of puncture site vascular complications
- Higher BMI
- OR 1.23 (1.04-1.50) (95% CI)
- Prostar vs ProGlide
- OR 6.03 (2.23-16.30) (95% CI)
- MANTA vs ProGlide
- OR 6.18 (2.67-14.27) (95% CI)
Other independent predictor of non-puncture site vascular complications
- Female sex
- OR 2.69 (1.12-6.42) (95% CI)
Original publication
Impact of Severity and Extent of Iliofemoral Atherosclerosis on Clinical Outcomes in Patients Undergoing TAVR. JACC Cardiovasc Interv. Published 9 October 2024. doi:10.
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