Heart failure & cardiomyopathies

Implementing a Cardiology Quality Incentive Program to Improve Guideline-Directed Medical Therapy

JACC AdvPublished interrupted time series analysis

Main finding · Composite HFrEF therapy metricResult — go to the result2-year odds ratio 2.285 95% CI 1.653–3.158

Authors' conclusion

Our program was associated with sustained improvements in GDMT adherence for CVD. It may serve as a scalable model for enhancing the quality of cardiovascular care.

Study context

Population
Cardiologists and their individualized cardiovascular disease (CVD) patient panels in ambulatory clinics of an academic health systemcardiologists across 15 ambulatory clinics
Participants
54 cardiologists
Comparison
Monthly, 1-year, and 2-year changes in the odds of adhering to each specific metric associated with the implementation of the cardiovascular population health program
Outcome
Composite HFrEF therapy metric
Follow-up
2 years
Methodological details15 ambulatory clinics, academic health system
  • 15 ambulatory clinics
  • Academic health system

Main finding

As reported in the abstract

2-year odds ratio

2.285

95% CI 1.653–3.158

P < 0.001

Cardiovascular population health program
2-year odds ratio 2.285 (95% CI 1.653–3.158); P < 0.001

Further findings

Mineralocorticoid receptor antagonist · 2 years

Comparison2-year OR (95% CI)P value
Cardiovascular population health programAfter vs before the intervention3.039 (2.520–3.663)P < 0.001

Specified beta blockers · 2 years

Comparison2-year OR (95% CI)P value
Cardiovascular population health programAfter vs before the intervention1.430 (1.129–1.810)P = 0.003

Angiotensin-converting enzyme inhibitor, angiotensin receptor blocker, or angiotensin receptor-neprilysin inhibitor therapy for heart failure with reduced ejection fraction (HFrEF) · 2 years

Comparison2-year OR (95% CI)P value
Cardiovascular population health programAfter vs before the intervention1.228 (1.001–1.505)P = 0.049

Statin or proprotein convertase subtilisin/kexin type 9 inhibitor therapy for atherosclerotic cardiovascular disease · 2 years

Comparison2-year OR (95% CI)P value
Cardiovascular population health programAfter vs before the intervention1.146 (1.092–1.202)P < 0.001

Blood pressure control · 2 years

Comparison2-year OR (95% CI)P value
Cardiovascular population health programAfter vs before the intervention1.496 (1.444–1.550)P < 0.001

Original publication

Implementing a Cardiology Quality Incentive Program to Improve Guideline-Directed Medical Therapy. JACC Adv. Published 20 June 2025. doi:10.1016/j.jacadv.2025.101879

Summarised from the published abstract; every number is checked against it

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