Arrhythmias & electrophysiology

Importance of Right Ventricular Mapping and Ablation for Ventricular Tachycardia in Postinfarction Patients

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

The arrhythmogenic substrate in PMI patients often involves the right ventricle, including the septum and free wall. The presence of RV dysfunction and greater LVEF were associated with the presence of RV free wall target sites. Patients with only RV septal target sites had worse postablation outcomes.

Study context

Population
Patients undergoing ablation for post-MI ventricular tachycardia (VT) with right ventricular (RV) target sitesof 277 PMI VT ablations
Participants
30 patients
Exposure
RV free wall vs septal VT target sites
  • Free walln = 10
  • Septaln = 20reference
Outcome
Characteristics by RV target site
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

RV dysfunction

P = 0.023

OutcomeFree wallSeptalP value
LVEF38.3% ± 21.06%23.9% ± 11.93%P = 0.02
RV target sites among PMI VT ablations
30 (11%)
VTs with RV targets induced
57

Observational data: associations, not effects.

Further findings

OutcomeP value
Survival free of VT, transplantation or LV assist device after ablation · mean follow-up 3.4 ± 3.2 yearsWorse with septal target siteslog-rank P < 0.05

Original publication

Importance of Right Ventricular Mapping and Ablation for Ventricular Tachycardia in Postinfarction Patients. JACC Clin Electrophysiol. Published 26 October 2022. doi:10.1016/j.jacep.2022.08.034

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