Arrhythmias & electrophysiology
Septal Substrate Ablation Guided by Delayed Transmural Conduction Times: A Novel Ablation Approach to Target Intramural Substrates
Authors' conclusion
In patients with NICM and ISS-VT, a substrate ablation strategy that incorporates areas of DCT appears to improve freedom from recurrent VT.
Study context
- Population
- Patients with nonischemic cardiomyopathy (NICM) and intramural septal substrate for VT (ISS-VT) referred for catheter ablation, 2016–2020
- Participants
- 57 vs 24
- Exposure
- Substrate ablation extended to DCT areas vs conventional substrate ablation
- Group 1n = 57reference
- Group 2n = 24
- Outcome
- Single-procedure VT-free survival
- Follow-up
- 12 months
Main finding
As reported in the abstract
P = 0.006
Observational data: associations, not effects.
Further findings
Noninducibility of any VT at end of ablation
P = 0.03
Time to VT recurrence · 12 months
P = 0.02
Original publication
Septal Substrate Ablation Guided by Delayed Transmural Conduction Times: A Novel Ablation Approach to Target Intramural Substrates. JACC Clin Electrophysiol. Published 19 July 2023. doi:10.
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