Heart failure & cardiomyopathies

Multiregional Implementation Initiative’s Impact on Guideline-Based Performance Measures for Patients Hospitalized With Heart Failure: IMPLEMENT-HF

Circ Heart FailPublished multiregional heart failure (HF) quality improvement initiative

Authors' conclusion

Among healthcare systems participating in IMPLEMENT-HF, there was a marked increase in QMT use among eligible patients over the course of the initiative. This quality improvement initiative supports a learning collaborative model to promote improvements in QMT use.

Study context

Population
Patients hospitalized with HF with reduced ejection fraction at hospitals participating in Get With The Guidelines-HF that volunteered for IMPLEMENT-HFadmitted patients at 61 hospitals
Participants
43,558 patients
Comparison
Quadruple medical therapy (QMT) utilization between Q1 2021 and Q2 2023
Outcome
Defect-free QMT at discharge
Follow-up
Q1 2021 to Q2 2023
Methodological details7 US regions, hospitals participating in the American Heart Association’s Get With The Guidelines-HF
  • 7 US regions
  • Hospitals participating in the American Heart Association’s Get With The Guidelines-HF

Main finding

As reported in the abstract

Q1 2021

4.7%

Q2 2023

44.6%

Further findings

Defect-free QMT at 30 days · Q1 2021 to Q2 2023

Q1 2021
0%
Q2 2023
44.8%
  • P <0.0001

Health-related social needs assessments

Substantially improved incorporation

Baseline characteristics

Median (interquartile range) age, years
74 (63-83)
Racial and ethnic minorities
16 530 (38%)
Women
22 228 (51%)

Improvements stratified by sex, race and ethnicity, and region

Magnitude of improvements similar when stratified by sex or race and ethnicity
Significant regional variation

Original publication

Multiregional Implementation Initiative’s Impact on Guideline-Based Performance Measures for Patients Hospitalized With Heart Failure: IMPLEMENT-HF. Circ Heart Fail. Published 21 March 2025. doi:10.1161/circheartfailure.124.012547

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