Acute cardiac care & resuscitation

In-Hospital and Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction Versus Heart Failure

Eur J Heart FailPublished Retrospective cohort study

Main finding · In-hospital mortalityResult — go to the resultAdjusted odds ratio 1.47 95% CI 1.43–1.52

Authors' conclusion

With medical advances during the past 10 years, the mortality of CS has decreased significantly, but the mortality of HF-CS remains high.

Study context

Population
Adults (≥18 years) with cardiogenic shock admitted to an ICU, Korean National Health Insurance Service database, 2010–2020
Participants
136,092 adults
Exposure
HF-CS vs AMI-CS
  • HF-CSn = 87,388
  • AMI-CSn = 48,704reference
Outcome
In-hospital mortality
Methodological detailspopulation-based, nationwide
  • Population-based
  • Nationwide

Main finding

In-hospital mortality

Adjusted odds ratio

1.47

95% CI 1.43–1.52

By group

HF-CS vs AMI-CS
adjusted OR 1.47 (95% CI 1.43–1.52)

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

OutcomeAMI-CSHF-CSEstimate
Cardiac replacement therapy (LV assist device implantation or heart transplantation)adjusted OR 1.65 (95% CI 1.16–2.34)
Follow-up mortality after successful discharge8.5%19.3%adjusted HR 1.54 (95% CI 1.48–1.59)
OutcomeAdjusted ratio (95% CI)
In-hospital medical costs0.79 (0.79–0.80)

Trends over the 10-year study period

In-hospital mortality rate decreased and actual medical costs tended to increase, regardless of cardiogenic shock (CS) aetiology

Original publication

In-Hospital and Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction Versus Heart Failure. Eur J Heart Fail. Published 10 June 2024. doi:10.1002/ejhf.3333

Summarised from the published abstract; every number is checked against it

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