Acute cardiac care & resuscitation
In-hospital cardiac arrest in neonates in the United States: a study of epidemiology, outcomes, and trends from 2003 to 2022
Authors' conclusion
The incidence of IHCA in neonates in the US has increased from 2003 to 2022, with a decrease in mortality during index admission. While the odds of IHCA is highest among EP and VP neonates, the majority of IHCA occurred in MP, LP, and T neonates. Mortality for EP, VP, and LP neonates has remained unchanged.
Study context
- Population
- Neonates (birth to 28 days of life) in US hospitals, 2003–2022
- Participants
- 24,877,754 discharges
- Outcome
- Incidence of and mortality after in-hospital cardiac arrest (IHCA)
- Follow-up
- Birth to 28 days of life
Methodological detailsKids' Inpatient Database, 7 one-year epochs
- Kids' Inpatient Database
- 7 one-year epochs
Main finding
As reported in the abstract
- Neonates with IHCA
- 30,117
- IHCA incidence per 1000 discharges
- 1.21
- IHCA incidence per 1000 US births
- 1.08
- Trend in IHCA incidence per 1000 discharges (increased)
- 0.8-1.58; p < 0.001
- Trend in mortality during index admission (decreased)
- 46.3-40.8 %; p = 0.005
Observational data: associations, not effects.
Further findings
Odds of IHCA by race and socioeconomic status
- Odds of IHCA higher in Black neonates and those at lower socioeconomic status
Original publication
In-hospital cardiac arrest in neonates in the United States: a study of epidemiology, outcomes, and trends from 2003 to 2022. Resuscitation. Published 11 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →