Acute cardiac care & resuscitation

Incidence, analysis and risk of out-of-hospital cardiac arrest in individuals with non-ischaemic dilated cardiomyopathy

ESC Heart FailPublished observational, register-based study with cohort and nested case-control analyses

Authors' conclusion

The Danish NIDCM population has a significantly increased incidence of OHCA compared to the general population but a comparable mortality despite multiple positive resuscitation characteristics.

Study context

Population
Individuals with non-ischaemic dilated cardiomyopathy (NIDCM) and the general population, Denmark's healthcare registers, 1 June 2001 to 31 December 2022
Comparison
NIDCM patients compared with the general population
Outcome
Incidence rate of OHCA
Methodological detailsnationwide, exposure-matched cohort
  • Nationwide
  • Exposure-matched cohort

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Risk of OHCA, de novo NIDCM vs non-NIDCM · 5 and 10 years · Aalen-Johansen estimator in an exposure-matched cohort

Male, 5-year

Male, 10-year

Female, 5-year NIDCM 1.4% · non-NIDCM 0.4

Female, 10-year

Initial shockable rhythm among OHCAs · higher with NIDCM · nested case-control study

P < 0.001

Mortality after OHCA · 30 day and 1-year

30 day

1-year NIDCM 82% · non-NIDCM 84

Mortality after out-of-hospital cardiac arrest (OHCA) · 30 day and 1-year

No significant differences

Original publication

Incidence, analysis and risk of out-of-hospital cardiac arrest in individuals with non-ischaemic dilated cardiomyopathy. ESC Heart Fail. Published 31 July 2026. doi:10.1093/eschf/xvag207

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