Heart failure & cardiomyopathies
Incidence of Atrial Fibrillation in Patients with an Insertable Cardiac Monitor and Symptomatic Heart Failure
Authors' conclusion
AF was observed in almost half of patients with ICM and symptomatic HF. One-fourth of the patients had new onset AF and a higher rate of HF events compared with patients without AF. AF incidence was similar in patients with preserved and reduced LVEF.
Study context
- Population
- Patients with an insertable cardiac monitor (ICM) and a clinical history of symptomatic heart failure (HF) with reduced or preserved left ventricular ejection fraction (LVEF), Optum EHR dataset merged with ICM device dataset, 2007–2021911 included (≥180 days follow-up)
- Participants
- 1,020 patients
- Exposure
- Reduced vs preserved LVEF
- Outcome
- Kaplan-Meier incidence of AF (AI model probability of AF ≥ 0.9)
- Follow-up
- 42 months
Methodological detailsreal-world, AI-adjudicated ICM-detected atrial fibrillation (AF) episodes
- Real-world
- AI-adjudicated ICM-detected AF episodes
Main finding
As reported in the abstract
Incidence of AF
- Incidence of AF, overall
- 45.6%
- Patients with true AF (8407 episodes)
- 358
Observational data: associations, not effects.
Further findings
New-onset AF (no clinical history of AF)
Longer duration paroxysmal AF
P = 0.02
| Outcome | OR (CI) | P value | |
|---|---|---|---|
| HF event rate: new-onset AFvs no history of AF and no AF during follow-up | 2.73 (1.47–5.09) | P = 0.002 | |
| 0.20.5125Odds ratio (log scale) |
- New-onset AF (no clinical history of AF) — Incidence of new-onset AF, overall
- 23.2%
Original publication
Incidence of Atrial Fibrillation in Patients with an Insertable Cardiac Monitor and Symptomatic Heart Failure. ESC Heart Fail. Published 9 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →