Valvular & structural heart disease
Incidence, Predictors, and Outcomes of Unplanned Coronary Angiography After Transcatheter Aortic Valve Replacement
Authors' conclusion
Unplanned angiography post-TAVR occurs in about 1 in 15 patients, with about one-half occurring within the first year, about one-half due to acute coronary syndrome, and pre-existing CAD being the strongest predictor.
Study context
- Population
- Patients undergoing transcatheter aortic valve replacement (TAVR), July 2015–December 2021
- Participants
- 1,444 patients
- Exposure
- Preprocedural coronary artery disease (CAD) vs Others
- Outcome
- Incidence, predictors and outcomes of unplanned coronary angiography after TAVR
Main finding
As reported in the abstract
Unplanned post-TAVR angiography
P < 0.001
- Unplanned post-TAVR angiography, overall
- 6.7%
- Within the first year
- 45%
- Indication ACS, overall
- 3.3%
Observational data: associations, not effects.
Further findings
Factors associated with unplanned angiography (multivariable)
| HR (95% CI) | P value | ||
|---|---|---|---|
| Age >75 years | 0.46 (0.30–0.71) | P < 0.001 | |
| Mean aortic valve gradient | 0.82 (0.68–0.98) | P = 0.031 | |
| Dialysis | 2.68 (1.07–6.74) | P = 0.036 | |
| CAD | 2.96 (1.76–4.98) | P < 0.001 | |
| 0.10.31310Hazard ratio (log scale) |
5-year prediction of unplanned angiography (multivariate models)
- AUC
- 0.71 to 0.77
Original publication
Incidence, Predictors, and Outcomes of Unplanned Coronary Angiography After Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv. Published 23 October 2024. doi:10.
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