Insomnia symptom trajectories and incident cardiovascular disease in older adults: a longitudinal cohort study
Authors' conclusion
Greater burden of insomnia symptoms at baseline and trajectories over time were associated with higher CVD incidence in older adults.
Study context
- Population
- Participants aged ≥50 years without baseline cardiovascular disease (CVD) from the US Health and Retirement Study (2002–2018)participants without baseline CVD
- Participants
- 12,102 participants
- Exposure
- Insomnia symptoms and their trajectories over time and incident CVD
- Outcome
- Incident CVD events
- Follow-up
- median of 10.2-year follow-up
Methodological detailspopulation-based cohort
- Population-based cohort
Main finding
As reported in the abstract
Incident CVD events
3962
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Incident CVD (heart disease or stroke) by number of insomnia symptomsOne symptomvs no symptomsAdjusted for sociodemographics, lifestyle and comorbidities | 1.16 (1.05–1.27) | |
| Incident CVD (heart disease or stroke) by number of insomnia symptomsTwo symptomsvs no symptomsAdjusted for sociodemographics, lifestyle and comorbidities | 1.16 (1.05–1.28) | |
| Incident CVD (heart disease or stroke) by number of insomnia symptomsThree to four symptomsvs no symptomsAdjusted for sociodemographics, lifestyle and comorbidities | 1.26 (1.15–1.38) | |
| Incident CVD by insomnia symptom trajectoryIncreasingvs persistent low | 1.28 (1.10–1.50) | |
| Incident CVD by insomnia symptom trajectoryPersistent highvs persistent low | 1.32 (1.15–1.50) | |
| 0.512Hazard ratio (log scale) |
Insomnia symptom trajectories identified
Original publication
Insomnia symptom trajectories and incident cardiovascular disease in older adults: a longitudinal cohort study. Heart. Published 27 May 2025. doi:10.
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