Heart failure & cardiomyopathies
The evaluation of copy number variants in an unselected population of patients with inherited cardiac conditions: the INTERACTION study
Authors' conclusion
Evidence from this real-world cohort suggests the incorporation of CNV analysis as a second-tier test in patients with ICC and specific clinical or molecular indications.
Study context
- Population
- ICC probands with prior negative or inconclusive SNV and InDel testing, Italy
- Participants
- 203 probands
- Outcome
- Prevalence of pathogenic CNVs
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Diagnostic yield of pathogenic CNVs
Diagnostic yield
0.50%
Observational data: associations, not effects.
Original publication
The evaluation of copy number variants in an unselected population of patients with inherited cardiac conditions: the INTERACTION study. Europace. Published 18 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →