Invasive Right Anomalous Coronary Arteries Assessment: Intravascular Ultrasound and Adenosine vs Dobutamine Fractional Flow Reserve
Authors' conclusion
In adults with newly diagnosed R-AAOCA and interarterial and intramural course, one-quarter were hemodynamically relevant. FFRAdenosine could reliably rule-in, while IVUS-MLA could effectively rule-out relevant R-AAOCA, potentially reducing the need for FFRDobutamine testing.
Study context
- Population
- Patients with right anomalous aortic origin of a coronary artery (R-AAOCA) and interarterial/intramural coursepatients included, 17 (23%) with hemodynamically relevant R-AAOCA
- Participants
- 73 patients
- Comparison
- Diagnostic accuracy of FFRAdenosine and IVUS-MLA against the reference standard of FFRDobutamine for identifying hemodynamically relevant R-AAOCA
- Outcome
- Hemodynamically relevant R-AAOCA (FFRDobutamine ≤0.80)
Methodological detailsconsecutive patients, prospectively enrolled
- Consecutive patients
- Prospectively enrolled
Performance
As reported in the abstract
Patients with hemodynamically relevant R-AAOCA
Seventeen patients (23%)
Further findings
Diagnostic performance for FFRDobutamine ≤0.80
Threshold FFRAdenosine ≤0.80 · IVUS-MLA ≤5.5 mm²
Specificity
Positive predictive value
Sensitivity
Negative predictive value
Area under the curve FFRAdenosine 0.81 · IVUS-MLA 0.88
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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