Arrhythmias & electrophysiology
Left atrial appendage closure in patients with left atrial appendage thrombus guided by intracardiac echocardiography
Authors' conclusion
LAAC using the LAmbre device guided by ICE may be feasible in patients with LAA thrombus when performed by experienced operators.
Study context
- Population
- Patients with persistent left atrial appendage (LAA) thrombus despite anticoagulation or contraindications to anticoagulation, June 2021–April 2023mean age 65 ± 7 years
- Participants
- 12 patients
- Outcome
- Feasibility of LAAC: periprocedural events and clinical outcomes during follow-up
Methodological detailssingle-group
- Single-group
Main finding
As reported in the abstract
Feasibility
- Device successfully implanted in all patients
- 12
- Severe periprocedural complications
- 0
- Thrombus location: apex
- 6
- Thrombus location: body
- 3
- Thrombus location: ostium
- 3
Observational data: associations, not effects.
Further findings
- No device-related thrombus or peridevice leak > 3 mm detected; all completed TEE follow-up
Safety
Stroke/TIA, systemic embolism or major bleeding · median follow-up 147 days (IQR 80-306 days)
- No patient experienced stroke/TIA, systemic embolism or major bleeding
Original publication
Left atrial appendage closure in patients with left atrial appendage thrombus guided by intracardiac echocardiography. Heart Rhythm. Published 23 January 2024. doi:10.
Summarised from the published abstract; every number is checked against it