Arrhythmias & electrophysiology
Left atrial shape as a marker of atrial myopathy in embolic stroke of undetermined source
Authors' conclusion
Alterations in LA shape are present in ESUS, AF, and CE patients, particularly increased spherical remodelling.
Study context
- Population
- Ischaemic stroke and atrial fibrillation (AF) patients and controls
- Participants
- 236 participants
- Exposure
- Left atrial (LA) shape by stroke cause vs AF patients and controls
- AFn = 81
- Embolic stroke of undetermined source (ESUS)n = 50
- CEn = 57
- Controlsn = 48reference
- Outcome
- LA shape/sphericity (3D LA sphericity; 2D-derived LA circularity, ellipticity, sphericity and eccentricity indices)
Methodological detailsK-means cluster analysis
- K-means cluster analysis
Main finding
As reported in the abstract
LA volume, function and sphericity
LA sphericity markers differentiated ESUS from controls (adjusted for age, sex, left ventricular (LV) and LA parameters)
P < 0.01
Observational data: associations, not effects.
Original publication
Left atrial shape as a marker of atrial myopathy in embolic stroke of undetermined source. Eur Heart J Cardiovasc Imaging. Published 15 March 2024. doi:10.
Summarised from the published abstract; every number is checked against it