Acute cardiac care & resuscitation

Left ventricular energetics in patients receiving veno-arterial extracorporeal membrane oxygenation for extracorporeal cardiopulmonary resuscitation

ResuscitationPublished Mechanistic study

Authors' conclusion

High VA-ECMO flow significantly reduced LVEDP, LVEDV, and LVSW compared to low VA-ECMO flow.

Study context

Population
Patients on veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for extracorporeal cardiopulmonary resuscitation (ECPR) who achieved return of spontaneous circulationevery patient studied at both flows
Participants
15 patients
Comparison
High vs low VA-ECMO flow
Outcome
LVEDV
Follow-up
3.0 (2.0, 4.0) days after cannulation
Methodological detailspaired comparisons, invasive left heart catheterization and 3D echocardiography
  • Paired comparisons
  • Invasive left heart catheterization and 3D echocardiography

Main finding

As reported in the abstract

P = 0.005

Further findings

OutcomeP value
LVEDP, highest vs lowest VA-ECMO flow (paired)LVEDP increased at low flowP = 0.001
LVSW, highest vs lowest VA-ECMO flow (paired)LVSW increased at low flowP = 0.01
  • Left ventricular end-diastolic pressure (LVEDP), highest vs lowest VA-ECMO flow (paired): Highest flow median 4.0 L/min; lowest flow median 2.0 L/min

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Left ventricular energetics in patients receiving veno-arterial extracorporeal membrane oxygenation for extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 19 December 2024. doi:10.1016/j.resuscitation.2024.110475

Composed by AI from the published abstract and checked against it. How Briefs are made →

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