Heart failure & cardiomyopathies

Length of Stay and Prior Heart Failure Admission in Frailty and Heart Failure: A Systematic Review and Meta-Analysis

ESC Heart FailPublished Systematic Review and Meta-Analysis

Pooled result · Length of stay (LoS)Result — go to the resultMean difference (MD) 3.67 95% CI 2.26–5.08

Authors' conclusion

Patients with frailty have longer LoS and more frequent HHF, underscoring the need for early, targeted interventions to manage frailty that may be attributed primarily to ageing and comorbidity-related status.

Study context

Population
Patients with heart failure, with versus without frailty
Comparison
patients with HF and frailty versus without frailty
Outcome
Length of stay (LoS)
Methodological detailsrandom-effects model
  • Random-effects model

Pooled result

Length of stay (LoS)

Mean difference (MD)

3.67

95% CI 2.26–5.08

P < 0.01

Frailty vs without frailty
mean difference (MD) 3.67 (95% CI 2.26–5.08); P < 0.01

As reported in the abstract

Further pooled results

OutcomeOdds ratio (OR) (95% CI)P value
Prior hospitalization due to heart failure (HHF) · n = 17; I2 = 81%1.76 (1.50–2.07)P < 0.01

Risk of bias and publication bias

Egger's test showed publication bias regarding studies that examined length of stay (LoS)
P = 0.02
Risk of bias assessment of the included studies was overall fair

Original publication

Length of Stay and Prior Heart Failure Admission in Frailty and Heart Failure: A Systematic Review and Meta-Analysis. ESC Heart Fail. Published 10 April 2025. doi:10.1002/ehf2.15300

Summarised from the published abstract; every number is checked against it

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.